Job Description

Location: Lexington, MA
Employment Type: Full-Time
Website:

About Medicilon

Medicilon is a global Contract Research Organization (CRO) providing integrated drug discovery and preclinical development services to pharmaceutical and biotechnology companies worldwide. Our U.S. research facility in Lexington, Massachusetts supports clients across a range of preclinical pharmacology and drug development programs.

Position Summary

Medicilon USA is seeking a Research Associate II – In Vivo Pharmacology to support preclinical pharmacology and disease model studies at our Lexington, MA facility.

The successful candidate will have hands-on experience working with rodents in a CRO, biotechnology, pharmaceutical, or research environment. This is a hands-on laboratory position responsible for animal procedures, dosing, sample collection, study execution, and accurate data documentation.

Key Responsibilities

• Perform rodent handling, restraint, dosing, monitoring, and sample collection.
• Administer compounds through common routes including oral gavage, IV, SC, and IP.
• Prepare test article formulations and perform dose calculations according to study protocols.
• Perform blood collection, tissue collection, necropsy, and sample processing.
• Conduct protocol-specific assessments including body weights, clinical observations, disease scoring, and other in-life measurements.
• Support study setup and execution, including preparation of materials, labeling, room setup, and protocol review.
• Accurately document study procedures, observations, and data.
• Conduct work according to approved protocols, SOPs, IACUC requirements, and company policies.
• Monitor animal health and welfare and promptly communicate concerns.
• Maintain laboratory equipment, supplies, and study materials.
• Work closely with scientists and project teams to meet study timelines and deliverables.
• Participate in training and development of additional in vivo techniques.
• Perform other related duties as assigned.

Qualifications

Required:

• Bachelor's degree in Biology, Animal Science, Life Sciences, or a related field.
• Approximately 2+ years of hands-on in vivo experience in a CRO, biotechnology, pharmaceutical, academic, or similar research environment.
• Hands-on experience with rodent handling, restraint, dosing, and animal monitoring.
• Experience with common dosing and sample collection techniques.
• Experience following study protocols and maintaining accurate research documentation.
• Understanding of laboratory animal welfare and IACUC requirements.
• Strong attention to detail, organization, and communication skills.
• Ability to work effectively in a fast-paced, team-oriented laboratory environment.

Preferred:

• Experience with oral gavage, IV, SC, and IP dosing.
• Experience with blood collection, tissue collection, necropsy, and sample processing.
• CRO or pharmaceutical industry experience.
• Experience supporting pharmacology, efficacy, PK/PD, or disease model studies.
• Experience with immunology, inflammation, metabolic disease, fibrosis, or other non-oncology disease models.
• ALAT certification or equivalent laboratory animal training.
• GLP experience.
• Experience with specialized in vivo techniques, surgical support, telemetry, or advanced disease model assessments.

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